Manager Steve Bruce has left Newcastle United by mutual consent just 13 days after the Saudi Arabia-backed £305m takeover of the club was completed.
The 60-year-old took charge of his 1,000th match as a manager in Sunday's 3-2 defeat by Tottenham - his only game as Magpies boss under the new owners.
Bruce said there had been "highs and lows" and that he hoped the new owners could "take the club forward".
Newcastle said the appointment of a new manager "will be announced in due course".
Graeme Jones will take interim charge of the Premier League side.
Bruce was appointed Magpies manager in July 2019 and achieved finishes of 13th and 12th in his two full seasons in charge.
I would like to thank my coaching team, the players and the support staff for all their hard work.
This is a club with incredible support, and I hope the new owners can take it forward to where we all want it to be. I wish everyone the very best of luck for the rest of this season and beyond.
I was so proud to be manager of Newcastle United, even in the dark times, I was determined to keep going and to keep this club in the Premier League.
A Newcastle statement said the club "would like to place on record its gratitude to Steve for his contribution and wishes him well for the future".
Bruce had a 27.4%-win percentage from 84 league games at Newcastle, which was the ninth best compared to previous Magpies managers who had overseen at least 20 Premier League matches.
The club's next game will be at Crystal Palace at 15:00 BST on Saturday, 23 October.